Chapter 22-24

Which of the following are essential regulators of normal cellular functions?

• carcinogenic agents

• protoncogenes

• tumor suppressor genes

• oncogenes

Which of the following is NOT an antitumor antibiotic?

• Blenoxane

• Vinblastine

• Adriamycin

• Cerubidine

Mitotic inhibitors are referred to as which of the following?

• alkyl sulfonates

• antitumor antibiotics

• antimetabolites

• plant alkaloids

Chemotherapy kills cancer cells because of its ability to:

• synthesize RNA

• synthesize DNA

• stop cell division

• increase cell division

Alkylating agents cause hydrogen replacement by an alkyl group, specifically one that inhibits cell division and growth. The five major types of alkylating agents include nitrogen mustards and all the following except:

• ethyleneimines

• nitrosoureas

• triazenes

• antimetabolites

Doxorubicin is used to treat which of the following cancers?

• breast and ovarian

• Kaposi's sarcoma and Wilms' tumor

• testicular and urinary bladder

• skin and brain cancer

Which of the following hormones is used to treat prostate cancer?

• estrogen

• androgen

• progestin

• testosterone

Basic structural subunits of DNA whose precise sequencing encodes the DNA are known as:

• nitrosoureas

• cell-cycle phase specific agents

• tumor cells

• nucleotides

Make sure patients understand that mitotic inhibitors may produce serious toxicity with GI damage and:

• increased bone formation

• the migration of WBCs

• bone-marrow depression

• blocked hormone action

Cancer treatments made from natural products produced by Streptomyces are known as:

• interferons

• biologic-response modifiers

• antitumor antibiotics

• hormonal agents