Biology Paper 4

Explain the meaning of the term Restriction Endonuclease and state it's role during the production of insulin by genetic engineering (4 marks)

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Cystic Fibrosis (CF) is an inherited disease. Explain briefly how two parents who do not have CF may have a child with CF (2 marks)

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Describe the ways in which CF affects the lungs (2 marks)

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One potential way of treating CF is by using gene therapy. Outline, with reference to CF, what is meant by gene therapy. (2 marks)

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Describe one possible advantage and one possible disadvantage of using gene therapy to treat CF (2 marks)

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Outline the principles of Gel Electrophoresis (4 marks)

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Define the term BIOINFORMATICS (2 marks)

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Explain the properties of plasmids which make them suitable for use during genetic engineering (3 marks)

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