pharmaceutical analysis

1. Chromatography is a physical method that is used to separate and analyse __________

• simple mixtures

• complex mixtures

• viscous mixtures

• metals

In chromatography, the stationary phase can be ___________ supported on a solid.

• Solid or liquid

• Liquid or gas

• Solid only

• Liquid only

Which of the following cannot be used as adsorbent in Column adsorption chromatography?

• magnesium oxide

• silicagel

• Alumina

• Potassium permanganate

In chromatography, which of the following can the mobile phase be made of?

• Solid or liquid

• Liquid or gas

• Gas only

• Liquid only

In Thin layer chromatography, the stationary phase is made of _________ and the mobile phase is made of _________

• Solid, liquid

• Liquid, liquid

• Liquid, gas

• Solid, gas

In which of the following type of paper, chromatography does the mobile phase move horizontally over a circular sheet of paper?

• Ascending paper chromatography

• Descending paper chromatography

• Radial paper chromatography

• Ascending – descending chromatography

Which of the following steps takes place after injection of feed in Column chromatography?

• Detection of components

• Separation in column

• Elution from the column

• Collection of eluted component

Components with the strong attraction to the support move more slowly than components with weak attraction.

• true

• false

What happens during the ‘elution from the column’ phase chromatography?

• Components with the greatest affinity elute first

• Components with least affinity elute first

• Components elute in a random manner

• Components elute according to their concentration in the mixture

Given below is a diagram of separation of two components of a mixture in a chromatographic column. From the diagram, infer which component has a lesser affinity to the stationary phase.

• W

• X

• Y

• Z