Immunology

Autocrine signalling happens during ------------------- of T helper cells

• MHC II binding with TCR

• Synthesis of CD28

• Differentiation of T helper

• None of the above

Tags

NGSS.HS-LS1-4

Name a costimulatory molecule in T helper activation

(a)  

Signal 0 is ----------------------

• Binding of antigen to MHC II in APC

• Presence of specific molecular patterns in presented antigens

• Phagosome formation

• Transfer of T cells to Secondary lymphoid organs

Conditions required for successful activation of T helper

• Presence of signal 0

• Presence of inadequate amount of CD28

• Presence of CD80 or CD86 in APC

• Formation of microclusters of TCR complex in T helper

Examples for professional APCs

• T lymphocytes

• Dendritic cells

• B lymphocytes

• Erythrocytes

Signal II leads to anergy or inactivation of T helper when

• Inadequate quantity of CD28 is expressed

• The APC is presenting an autoantigen

• Signal 0 is present

• Competitive binding of CTLA 4 with CD80 or CD86

A T lymphocyte which has not encountered an antigen yet

• Novice

• Small

• Stem

• Naive

The T helper releases a ------------------- during autocrine signalling

• IL-2

• IL-3

• IL-1

• IL-R

The signal helping in verification of the presented Antigen as self or non self

• Signal 0

• Signal 1

• Signal 2

• Signal 3

The CD4 is present as part of -------------- in T lymphocytes

• CD28 R

• TCR complex

• Microcomplex

• ILR complex