ADR Violet 101-200

101. Cholestyramine can bind with digoxin. Which of the following is TRUE regarding this drug interaction?<br /><br />I. Cholestyramine is the object drug<br />II. Digoxin is the precipitant<br />III.Digoxin is the object drug

• A. I only
• B. III only
• C. I and II only
• D. II and III
• E. I, II and III

102. Which of the following is paired correctly?

• A. Tetracycline -object drug Antacid – precipitant drug
• B. Ciprofloxacin – precipitant Milk – object drug
• C. Cimetidine – object drug Atorvastatin – precipitant drug
• D. Tetracycline – precipitant Antacid – object drug
• E. Penicillin – precipitant Probenecid – object drug

103. A patient asks you about using Coenzyme Q10 since he has read about its benefits in a magazine. Further interview of the patient revealed that he is maintained on 2 mg daily dose of warfarin. What would be the recommendation for this patient?

• A. There is no reason for concern, the patient could take Coenzyme Q10
• B. Coenzyme Q10 may antagonize the activity of warfarin, use of which warrants a consult with the doctor
• C. Warfarin antagonizes the effect of Coenzyme Q10, do not take warfarin
• D. Tell the patient to tell the doctor to remove his warfarin so he could take Coenzyme Q10
• E. It is not safe to take both medications together, so stop taking warfarin before taking Coenzyme Q10

104. A patient comes in complaining that the diazepam that was dispensed to him was not working. Upon reviewing the patient profile and further interview, it was revealed that the patient still has not stopped smoking despite the doctor’s and your recommendations to do so. What could be the cause for the patient’s complaint?

• A. Smoking does not affect the activity of diazepam. There might be another reason.
• B. Smoking decreases the activity of diazepam by inducing its metabolism
• C. Smoking decreases the activity of diazepam by inhibiting its metabolism
• D. Smoking increases the activity of diazepam, by inducing its metabolism
• E. Alcohol decreases the activity of diazepam by inhibiting its metabolism

105. A safety technique observed in community pharmacies to minimize medication errors.<br /><br />I. Organized and simplified work procedures<br />II. Working on one prescription at a time, instead of handling several prescriptions at once.<br />III.Using a magnifying lens when necessary

• A. I only
• B. III only
• C. I and II only
• D. II and III
• E. I, II and III

106. Purpose of auxillary labels, EXCEPT

• A. Ensure proper use of medications
• B. Reinforce information given during counselling
• C. To minimize verbal patient counselling
• D. Ensure proper storage of the medication
• E. Warm against taking with food or other drugs

107. An alcoholic taking paracetamol 500 mg every 6 hours prn back pain, is exposed to:

• A. Increased risk of renal toxicity
• B. Increased risk of hepatotoxicity
• C. Increased risk of photosensitivity
• D. Decreased effect of paracetamol
• E. All of these

108. A patient refills a prescription for oral contraceptives. You recall seeing this patient in the parking lot smoking cigarettes with a couple of friends a few minutes before she came into the pharmacy. This patient is at an increased risk for developing

• A. Cardiovascular disease
• B. Hepatic disease
• C. Lung disease
• D. Renal disease
• E. There is no reason for concern regarding this patient

109. A monitoring parameter for a patient on warfarin therapy

• A. ANC
• B. CBC
• C. ECG
• D. INR
• E. Platelet count

110. A patient comes to you complaining of sleepiness, feeling lethargic, and seems like not in the mood to do anything. Which of the following medications that the patient is currently on could cause the patient’s complaints?

• A. Gabapentin
• B. Lorazepam
• C. Hydrocodone/Acetaminophen
• D. All of these
• E. None of these