BB FINAL EXAM

American Association of Blood Bank Standards requires

that plateletpheresis products:

• Prepared in a closed system be transfused within 24 hours

• Contain 3x10¹¹ platelets in ≥ 90% of the units teste

• Have a compatibility test performed before transfusion

• Have a pH of 6.2 or greater on the day of collection

Therapeutic cytapheresis is used in patients with:

• Sickle cell disease to reduce the number of crises

• Systemic lupus erythematosus to remove immune complexes

• Leukemia to help increase granulocyte production

• Myasthenia gravis to increase antibody production

The minimum interval allowed between plateletpheresis

component collection procedures is

• 24 hours

• 48 hours

• 7 days

• 8 weeks

In plasma exchange, the therapeutic effectiveness is:

• Greatest with the first plasma volume removed

• Affected by the type of replacement fluid used

• Enhanced if the unwanted antibody is IgG rather than IgM

• Independent of the use of concomitant immunosuppressive therapy

The most common adverse effect of plateletpheresis collection is

• Allergic reactions

• Hepatitis

• Hemolysis

• Citrate effect

• Air embolism

Apheresis can be used to collect all of the following except:

• Leukocytes

• Macrophages

• Hematopoetic progenitor cells

• Platelets

• Lymphocytes

Transfused plasma constituents resulting in immediate erythema, itching, and hives best typify which of the following transfusion reactions

• HTR

• DHTR

• Allergic

• Iron overload

• Alloimmunization

Which listed transfusion reaction may result from an anamnestic response following a secondary exposure to

donor RBCs?

• IHTR

• Alloimmunization

• Anaphylactoid reaction

• TACO

• TA-GVHD

Patients at greatest risk of developing TACO may include:

• Children

• Elderly people

• Patients with chronic normovolemic anemia

• Patients with sickle cell disease

• All of the above

Which listed transfusion reaction is most associated with transfused patients lacking IgA immunoglobulin?

• Anaphylactic

• Hemolytic

• Febrile

• TACO