Oral microbiology and immune response

The main antibody found in the oral cavity is ....

• IgG

• IgM

• sIgA

• IgE

It is a calcium and zinc-chelating protein

• lysozyme

• calprotectin

• agglutinin

• histatin

It lyse bacterial cell by activating autolysin in the bacterial cell wall

• peroxidase

• lactoferrin

• lysozyme

• sIgA

It bind iron and make it unavailable to invading microbe

• mucin

• cystatin

• histatin

• lactoferrin

It hydrate and lubricate oral mucosa

• defensin

• agglutinin

• lysozyme

• mucin

It protect enamel from tooth-tooth and tooth-mucosa friction

• Peroxidase

• secretory leukocytes protease inhibitor

• agglutinin

• acquired enamel pellicle

Regarding commensal oral microbiota

• contribute to host nutrition through the synthesis of vitamins

• allows colonization of pathogenic bacteria

• produce antagonist to inhibit susceptible extrinsic bacteria

• contribute to immunity by inducing low level of circulating and secretory antibodies

Regarding sIgA

• prevent microbial adherence on mucosal surfaces

• bind free iron in saliva

• maintain integrity of the epithelial barrier

• bind to acquired pellicle thus aid in bacterial attachment to tooth surface for aggregation of bacteria

Regarding Von Ebner Gland Protein

• is secreted from Von Ebner Gland

• also secreted from minor gland in labial mucosa

• is cysteine protease inhibitor

• it involve in demineralization process

Regarding characteristic of salivary mucin.

• highly soluble

• strong adhesiveness

• low elasticity

• high viscosity