transfusion reactions

What component is most frequently involved with

transfusion-associated infection?

• Plasma

• Packed red blood cells

• Platelets

• Whole blood

Irradiation of blood is performed to prevent?

• Febrile non-haemolytic transfusion reaction

• acute haemolytic reaction

• transfusion associated graft vs host disease

• Sepsis

Donor history is a key method to reduce the risk of transfusion associated infections

• True

• False

What is the first step in investigating a possible transfusion reaction

• Clerical check

• Haemolysis check

• Direct antiglobulin test

• ABO test

Case study: Patient is suspected of having a transfusion reaction 10 minutes after the onset of RBC transfusion. What could possibly cause the transfusion reaction

• GVHD

• TRALI

• TACO

• allergic reaction

Case study: 57-year-old female bone marrow transplant (BMT) patient with non-Hodgkin’s lymphoma required transfusions on a regular basis due to her chronic anemia. During one of her transfusion visits to the clinic, the patient developed a 1.8°C increase in temperature with sudden feeling of cold and sweating. Nurses stopped transfusion and performed a clerical check and found no discrepancy. Physician then requested a transfusion reaction workup. What does the workup include? Chose all correct answers

• ABO test

• Direct antiglobulin test (DAT)

• Check haemolysis

• Full antibody panel

Same case study: Patient was O Neg

DAT: Neg

No haemolysis

What should be done next?

• Perform full antibody panel

• Perform culture test

• notify physician of results and do nothing else

• resume transfusion

Same case study: Patient continued to present with high temperature and had also developed decreased blood pressure. Physician requested culture test which turned up positive with Gram positive cocci. What does that mean?

• Transfusion associated bacterial infection

• Transfusion associated viral infection

• Patient has a NON transfusion associated bacterial infection

What is the most likely cause of Staphylococci contamination of blood products?

• donor history was not accurate

• donation bag was contaminated

• donor testing was not carried out per standard procedure

• donor arm was not cleaned

  per standard operating procedures,