Lipid Metabolism

1/ In what compartment does the de novo fatty acid synthesis occurs?

• A) Mitochondria

• B) Perioxosome

• C) Cytosol

• D) Endoplasmic reticulum

2/  Long chain fatty acyl CoA are transported across the mitochondrial membrane by ?

• A) Carnitine

• B) caroten

• C) Choline

• D) creatine

3/ End product of B-oxidation of fatty acid with even number of carbon atoms is:

• A) Propionyl CoA

• B) Acetyl CoA

• C) Acetoacetyl CoA

• D) a-keto glutarate

4/ How many ATP molecules produces from B-oxidation of palmitylCoA?

• A) 131

• B) 100

• C) 90

• D) 129

5/ Dietary fats after absorption appear in the circulation as?

• A) VLDL

• B) LDL

• C) HDL

• D) Chylomicron

6/ Fatty acids are break down mainly by:

• A) HMP shunt

• B) beta-oxidation

• C) Lipogenesis

• D) alpha-oxidation

7/ In the Microsomal system two carbon atoms are added in the form of ……. As for Mitochondrial system carbon atoms were add in the form of ……… ?

• A) malonyl , acetyl-CoA

• B)  Propionyl CoA , acyl-CoA

• C) acyl-CoA , acetyl-CoA

• D) Acetoacetyl CoA, a-keto glutarate

8/ The conversion of acetyl CoA to malonyl CoA is the rate limiting step in fatty acid synthesis. Which of the following enzyme catalyzes the above mentioned reaction?

• A) Acetyl CoA decarboxylase

• B) Malonyl CoA synthetase

• C) Malonyl CoA synthase

• D) Acetly CoA carboxylase