Kidney tumours

1. Most common histologic type of RCC

• Papillary

• Clear cell

• Chromophobe

• Sarcomatoid

2. RCC with excellent prognosis

• Clear cell type

• Chromophobe type

• Papillary type

• Sarcomatoid

3. Psammomabodies are seen in ---------RCC

• Clear cell RCC

• Papillary RCC

• Chromophobe RCC

• Collecting duct RCC

4. Sarcomatoid change in RCC indicates

• Good prognosis

• Worse prognosis

5. Characteristic gross appearance of RCC

• Homogenous grey white

• Variegated

• Mahogany brown

6. Most common site of metastasis in RCC

• Liver

• Lungs

• Bones

• Brain

7. RCC has a characteristic tendency to invade

• Renal vein

• Renal artery

• Aorta

8. Papillary variant of renal cell carcinoma is associated with

• VHL gene mutation

• Monosomy 1

• Trisomy 7 & 17

• Hypodiploidy

9. Mention the false statement regarding renal cell carcinoma

• Most of them are sporadic

• Female predominance

• Clear cell carcinoma associated with VHL gene mutation

• Papillary RCC associated with MET protooncogene

10. In hereditary renal cell carcinoma (RCC), the following syndrome is implicated in carcinogenesis:

• Polycystic kidney disease

• Alports syndrome

• VHL syndrome

• Fabrys disease