Genetically Engineered Insulin

C-peptide of human insulin is:

• A part of mature insulin molecule

• Responsible for formation of disulphide bridges

• Removed during maturation of pro-insulin to insulin

• Responsible for its biological activity.

Insulin is synthesized by

• Beta cells of pancreas

• Alpha cells of pancreas.

• Delta cells of pancreas

• Hepatocytes

Glycogenesis is metabolic conversion of ....... into ...... while gluconeogenesis is the formation of ........

• 1. glycogen into glucose

  2. Glucose

• 1. glucagon into glucose

  2. Glucagon

• 1. glucose into glycogen

  2. Glucose from non-carbohydrate sources.

• 1. glucose into glucagon

  2. Glycogen

Human insulin was first produced by

• FG Banting

• Eli Lilly 

• Charles Best 

• John Macleod

The two DNA sequences corresponding to A and B peptide chains of human insulin is introduced in plasmids of …… to produce insulin chains.

• Streptococcus  sp.

• Hemophilus  sp. 

• Escherichia coli 

• Plasmodium sp.