Hemostatis

On this diagram summarizing the main steps or hemostasis, what A and B could be?

• Fibrinogen

• VWF ( von wildebrand factor)

• Collagen

• Prothrombin

• Thromboxane A2

Answer explanation

On this diagram summarizing the main steps or hemostasis, what is C?

• Fibrinogen

• VWF ( von wildebrand factor)

• Collagen

• Prothrombin

• Thromboxane A2

Answer explanation

On this diagram summarizing the main steps or hemostasis, what is D?

• Fibrinogen

• VWF ( von wildebrand factor)

• Collagen

• Prothrombin

• Thromboxane A2

Answer explanation

On this diagram summarizing the main steps or hemostasis, what is E ?

• Fibrinogen

• Fibrin

• thrombin

• Prothrombin

• Thromboxane A2

Answer explanation

On this diagram summarizing the main steps or hemostasis, what is G ?

• Fibrinogen

• Fibrin

• thrombin

• Prothrombin

• Thromboxane A2

Answer explanation

Citrate is often used as an anticoagulant. What part(s) of the hemostasis pathway does it inhibits ?

• various members of the Coagulation cascade ( factor I, II, etc…)

• Prothrombin synthesis

• Thrombin activity

• Thromboxane A

Answer explanation

EDTA is often used as an anticoagulant. What part(s) of the hemostasis pathway does it inhibits ?

• Various member of the Coagulation cascade ( factor I, II, etc…)

• Prothrombin synthesis

• Thrombin activity

• Thromboxane A

Answer explanation

Warfarin is often used as an anticoagulant. What part(s) of the hemostasis pathway does it inhibits ?

• Any member of the Coagulation cascade ( factor I, II, etc…)

• Prothrombin synthesis

• Thrombin activity

• Thromboxane A

Answer explanation

Warfarin inhibits the recycling/activation of vitamin K in the liver. Vitamin K is vital for the formation of clotting factors II (thrombin), VII, IX and X. It is often used as a blot clot preventative in at-risk patients.

It also inhibits the secretion of newly synthesized prothrombin by up to 73% over a 2-4 hours period (Karpatkin et al., Blood 1987)

Heparin is often used as an anticoagulant. What part(s) of the hemostasis pathway does it inhibits ?

• Any member of the Coagulation cascade ( factor I, II, etc…)

• Prothrombin synthesis

• Thrombin activity

• Thromboxane A

Answer explanation

Heparin activates antithrombin II, a natural inhibitor of thrombin.

Aspirin is often used as an anticoagulant. What part(s) of the hemostasis pathway does it inhibits ?

• Any member of the Coagulation cascade ( factor I, II, etc…)

• Prothrombin synthesis

• Thrombin activity

• Thromboxane A

Answer explanation

Aspirin affects the synthesis of Thromboxane A