Main types of trait inheritance

In autosomal dominant inheritance

• The disorder is observed in an equal number of females and males

• The disorder is observed in an equal number of females and males who are homozygous for

  the mutant gene

• the disorder is not passed from one generation to the next generation

• Both parents are obligate heterozygous carriers

Affected heterozygous mother and normal homozygous father

The genetic risk associated with an autosomal dominant disorder

is

• 50 %

• 100 %

• 25 %

• 0 %

Affected heterozygous mother and affected heterozygous father

The genetic risk associated with an autosomal dominant disorder

is

• 50 %

• 100 %

• 25 %

• 75 %

Affected homozygous mother and normal homozygous father

The genetic risk associated with an autosomal dominant disorder

is

• 50 %

• 100 %

• 25 %

• 75 %

In autosomal recessive inheritance

• Father-to-son transmission does not occur

• The disorder is observed in an equal number of females and males who are homozygous for

  the mutant gene

• the disorder is passed from one generation to the next generation

• The disorder is observed in twice the number of females than males

Normal heterozygous mother and normal heterozygous father

The genetic risk associated with an autosomal recessive disorder

is

• 50 %

• 100 %

• 25 %

• 75 %

Affected homozygous mother and normal homozygous father.

In autosomal recessive disorders, the genetic risk for the normal children

being heterozygous carrier is

• 50 %

• 100 %

• 0 %

• 66 %

Affected homozygous mother and normal homozygous father.

The genetic risk associated with an autosomal recessive disorder

is

• 50 %

• 100 %

• 25 %

• 0 %

Normal heterozygous mother and normal heterozygous father

In autosomal recessive disorders, the genetic risk for the normal children

being heterozygous carrier is

• 33 %

• 100 %

• 50 %

• 66 %

Affected homozygous mother and normal heterozygous father

The genetic risk associated with an autosomal recessive disorder

is

• 50 %

• 100 %

• 25 %

• 75 %