TA Section 2 (2/14)

All of the following are true EXCEPT:

• Gene expression involves transcription and translation

• Transcription copies DNA to RNA

• Translation copies RNA to protein

• All RNAs are translated into protein

These processes occur in the nucleus:

• Polyadenylation of 3'UTR

• 5' RNA capping

• Protein Translation

• RNA splicing

• RNA degradation

Answer explanation

Everything within the grey box occurs inside the nucleus. Processed RNAs leave the nucleus through nuclear pores. (Source: lecture 4, slide 5)

Ribose and deoxyribose differ at which carbon?

• 1'

• 2'

• 3'

• 4'

RNA capping, splicing, and polyadenylation factors can only bind to the tail of RNA Polymerase II when the tail is ____ by TFIIH.

• phosphorylated

• acetylated

• methylated

• cleaved

Answer explanation

Source: lecture 4, slide 7.

The RNA transcript matches the sequence of the

• non-coding strand

• coding strand

• both strands

• neither strand

In the ​ pre-mRNA, sequences that encode protein are ​ (a)   and the non-coding sequences are ​ (b)   .

• exons
• introns

The ribosome is made up of protein and ribozymes, which are...

• RNAs that carry an anticodon sequence and an amino acid

• proteins that specifically bind RNA

• RNAs with catalytic functions

The energy for phosphodiester bond formation comes from

• peptide bonds

• the phosphoanhydride bond of the nucleotide

• RNA polymerase

• no energy is required

The spliceosome catalyzes the removal of introns from the pre-mRNA. It is made up of snRNPs. snRNPs are...

• short RNA sequences

• small proteins

• nucleases

• RNA-protein complexes

RNA polymerase binds at the

• Transcription start site

• Promoter

• Terminator sequence

• Activator