Kohler - CFU Questions

To begin, George J.F ​ (a)   was born on April 17th, ​ (b)   in ​​ (c)   , and his nationality is German. Kohler attended the High School Progymnaisum Kehl a Rhein in where his performance was ​ (d)   excellent. He would not do work in his classes, the only thing he cared about was doing ​ (e)   .

• Kohler
• 1946
• Germany
• not
• sports

True or False

The following two statements are both true about Kohler:

Born: 17 April 1947, Munich, Germany

Died: 10 March 1995, Freiburg im Breisgau, Germany

• True

• False

True or False

The following two statements are both false about Kohler:

Born: 17 April 1947, Munich, Germany

Died: 10 March 1995, Freiburg im Breisgau, Germany

• True

• False

Match the picture with the correct name of the Scientist.

• Gilbert

• 
• Beadle

• 
• Jerne

• 
• Weller

• 
• Kohler

• 

Then, in ​ (a)   , he left school with a baccalaureate and went to study ​ (b)   at the University of Freisburg. At first, George actually wanted to become a High School ​ (c)   , and even took classes to become a professor. ​ ​ (d)   , he ended up changing ​ (e)   paths because he wanted to pursue a diploma in an academic or professional career.

• 1965
• Biology
• teacher
• However
• career

Education and research experience of Georges J.F. Köhler. Match the year with what Kohler accomplish that year.

• April 1976 to present

• Diploma in Biology, work on repair-deficient strains of Escherichia coli and computer assisted instruction.

• April 1965

• Abitur in Kehl, beginning of studies in Biology at the University of Freiburg.

• April 1974

• Postdoctoral work in cell biology (lymphocyte fusion) in Dr. C. Milstein’s laboratorium at the Medical Research Council, Laboratory of Molecular Biology. Work supported by an EMBO long-term fellowship. Publication: G. Köhler and C. Milstein (1975) “Continuous cultures of fused cells secreting antibody of predefined specificity”. Nature 256:495-497.

• April 1974 to March 1976

• Ph.D., University of Freiburg. Thesis work on immunological studies of the enzyme ß-galactosidase, carried out at the Institute for Immunology, Basel, Switzerland, under the supervision of Professor Fritz Melchers.

• January 1971

• Member of the Basel Institute for Immunology; Molecular and cellular work on lymphocyte hybrids.

Prize motivation: “for _______ concerning the specificity in development and ________ of the _______ system and the __________ of the principle for ___________ of monoclonal antibodies”

Kohler's Work according to The Nobel Prize Website:

The immune system includes ​ (a)   , lymphocytes and ​ antibodies that neutralize substances foreign to the body, or antibodies. We have millions of different antibodies, but each cell can produce only one kind of ​ (b)   Sometimes a cell that forms a certain kind of antibody grows abnormally and a ​ (c)   is formed. In 1975 George Köhler and Cesar ​ (d)   developed a method for combining such tumor cells with cells that are immune to a certain antigen so that antibodies of the same type—​ (e)   antibodies—can be produced.

• cells
• antibody.
• tumor
• Milstein
• monoclonal