Pharmacology 1 quiz(2)

An 18-year-old female patient is brought to the

emergency department due to drug overdose. Which

of the following routes of administration is the most

desirable for administering the antidote for the drug

overdose?

• Intramuscular.

• Subcutaneous.

• Transdermal.

• Oral.

• Intravenous.

Isoproterenol produces maximal contraction of cardiac

muscle in a manner similar to epinephrine. Which of the

following best describes isoproterenol?

• Full agonist.

• Partial agonist.

• Competitive antagonist.

• Irreversible antagonist.

• Inverse agonist.

The β-adrenoreceptor is an example of which type of receptor?

• G-protein coupled receptor

• Tyrosine kinase receptor

• Voltage-gated ion channel

• Ligand-gated ion channel

Which of the following statements explains receptor affinity?

• It is half the dose needed for maximal response

• It is a measure of how tightly a ligand binds to a receptor.

• It is the maximum response downstream of a receptor.

• It is the concentration of ligand that causes side effects.

When does tachyphylaxis occur?

• When there is a decreased receptor-mediated response to a drug.

• When there is an increased risk of side effects occurring.

• When smaller doses cause an increased response to a drug

• When the drug causes a faster heart rate

what is the type of the ligand in this figure ?

• Agonist

• Antagonist

• partial agonist

• None of the above

What is the type of the ligand in the following figure

• Agonist

• Antagonist

• inverse agonist

• None of the above