Antifungal drugs

Which of the following drugs has the mechanism of action involved in the inhibition of the synthesis of β-glucan, an essential constituent of a fungal cell wall?

• Amphotericin B

• Caspofungin

• Fluconazole

• Flucytosine

• Griseofulvin

Which of the following drugs can bind to cell membrane components by hydrophilic groups present in the drug molecule, resulting in the formation of pores?

• Caspofungin

• Flucytosine

• Griseofulvin

• Nystatin

• Terbinafine

Which of the following drugs was approved for systemic drug for superficial fungal infections and the mechanism of action of this drug is binding to microtubule and inhibition of cell division?

• Amphotericin B

• Clotrimazole

• Flucytosine

• Caspofungin

• Griseofulvin

A 35-year-old man with a history of AIDS was recently diagnosed as of cryptococcal meningitis.  Which of the following drugs is the most appropriate for the treatment of this patient?

• Ketoconazole

• Flucytosine

• Fluconazole

• Griseofulvin

• Caspofungin

Which of the following drugs has the broadest antifungal spectrum but is used only in case of severe mycoses because of its toxicity?

• Amphotericin B

• Clotrimazole

• Flucytosine

• Caspofungin

• Ketoconazole