Pharmacology Endocrine

Select the statement that best describes levothyroxine.

• It causes more adverse effects compared to liothyronine

• It can cause allergenicity.

• It is given orally in severe myxedema

• It is given in patients who undergone total thyroidectomy

The followings are adverse effect of thyroxine EXCEPT

• palpitation

• insomnia

• cold intolerance

• restlesssness

Select the advantage of T4 compared to T3

• T4 is more potent

• T4 has a long half life

• T4 can be given intravenously.

• T4 can be given to neonates.

Name the group agent X belongs to.

• Iodides

• Anion inhibitors

• Thioamides

• Beta blockers

A patient was scheduled for thyroidectomy. This agent is given as pre-operative medication.

• Potassium iodide

• Methimazole

• Anion inhibitor

• Radioactive iodine

Select the correct statement regarding radioactive iodine.

• Its effect is immediate.

• It inhibits thyroid hormone synthesis.

• It is contraindicated in pregnant women.

• It is useful in thyroid storm.

Select the advantage of PTU compared to methimazole in hyperthyroid patient who is pregnant.

• Propylthiouracil is accumulated in the thyroid gland.

• Propylthiouracil inhibits conversion of T4 to T3.

• Propylthiouracil does not readily cross the placenta.

• Propylthiouracil enables once daily administration.

Select the most likely treatment of thyroid storm:

• propranolol if patient has asthma

• Radioactive iodine to inhibit thyroid peroxidase enzyme

• Propylthiouracil to inhibit proteolysis

• potassium iodide to inhibit hormone synthesis

Patients having premature labour can be given this glucocorticoid for lung maturation of fetus

• Cortisone

• Prednisolone

• Betamethasone

• Fluticasone

Patients who had undergone adrenalectomy will be prescribed with this glucocorticoid

• Triamcinolone

• Hydrocortisone

• Dexamethasone

• Betamethasone