Lymphadenopathy and Leukemia

Which is the most common type of leukemia in children?

• Acute myeloid leukemia

• Acute lymphoblastic leukemia

• Chronic Myeloid Leukemia

• Chronic lymphocytic Leukemia

Where would you perform a bone marrow aspiration in a child?

• posterior superior iliac crest

• Sternum

• Humerus

• Femur

Which of the following genetic disorders is associated with increased risk of acute lymphoblastic leukemia?

• Thalassemia

• Daltonism

• Hemophilia

• Down syndrome

Which of the following is not consistent with the diagnosis of acute leukemia?

• Increased Hb for age

• Bone Pain

• Fever

• Reduced White Blood Cells

Clinical/US features worrisome for a malignant lymph node are all of the followings except for one...

• Supraclavicular localization

• Fixed nontender nodes

• oval or reniform in shape with an iperechogenic hilum 

• associated with reduced WBC, Hb and PLT

Histopathological hallmark of Hodgkin Lymphoma:

• Auer rods

• Reed Stemberg cell

• Lymphocyte infiltration

• Presence of CD20 at immunoistochemistry

Which of the following is a part of Acute promyelocytic leukemia therapy?

• all-trans-retinoic acid

• Vincristine

• Brentuximab Vedotin

• Nivolumab

How many morphological subtypes (FAB classification) of AML exist?

• 5

• 3

• 7

• 6

What is MRD in the setting of acute leukemia?

• Most represented disorder

• Megacaryocyte reduction with dysplasia

• Maximun radiation dose

• minimal residual disease

Which was the first chemotherapy drug discovered by Farber?

• Doxorubicin

• Methotrexate (amethopterin)

• Vincristine

• Blinatunomab