Cancer Biology_2023_Ch9_3377

Senescence is:

• Programmed cell death

• Cellular aging and loss of function

• Uncontrolled cell division

• DNA damage repair mechanism

Telomeres are:

• Enzymes that repair DNA damage

• Protective caps at the ends of chromosomes

• Proteins involved in cell cycle regulation

• Structures that promote cell division

The main function of telomeres is to:

• Prevent DNA damage

• Promote DNA replication

• Protect chromosomes from degradation and fusion

• Regulate cell growth and division

What happens to telomeres with each round of cell division?

• They lengthen

• They remain the same

• They become shorter

• They are rearranged

This enzyme is responsible for adding telomeric repeats to the ends of chromosomes.

• Telomerase

• DNA polymerase

• Ligase

• Helicase