Summer TA Section 4 (7/13)

Estrogen and insulin are examples of which type of cell communication?

• Endocrine

• Paracrine

• Neuronal

• Contact-dependent

Estrogen is a __ hormone and insulin is a __ hormone

• Steroid, steroid

• Steroid, peptide

• Peptide, steroid

• Peptide, peptide

Which of the following is the signal molecule in juxtacrine signaling?

• Acetylcholine

• EGF

• Delta

• Notch

Receptors for growth factors and peptide hormones are found

• In the cytoplasm

• On the nuclear membrane

• On the plasma membrane

• In the extracellular matrix

Which of the following hormones is derived form cholesterol and can diffuse across the plasma membrane?

• Adrenaline

• Cortisol

• Estradiol

• Insulin

Protein kinases

• Generate ATP

• Hydrolyze ATP

• Add a phosphate group

• Remove a phosphate group

GTP binds which subunit of the GPCRs?

• Alpha

• Beta

• Gamma

• Lambda

When acetylcholine binds to its GPCR,

• Na+ channels open

• Na+ channels close

• K+ channels open

• K+ channels close

Which of the following is a second messenger in the signaling cascade that results in glycogen breakdown?

• Adenylyl cyclase

• cAMP

• PKA

• Glycogen phosphorylase

Which of the following second messengers remains bound to the membrane?

• cAMP

• PLC

• IP3

• DAG