GBM-Quiz

The most common primary malignant brain tumor is -

• Meningioma
• CNS brain metastatic tumors
• Glioblastoma
• Oligodendroglioma

Which of the following statement is true-

• Temozolomide cannot be given concurrently with radiotherapy
• Temozolomide can be given as monotherapy in newly diagnosed GBM patients
• Bevacizumab is approved in treatment of newly diagnosed GBM patients
• All of the above

Which of the following statement is true- Confirm diagnosis of GBM can be done based on

• clinical features
• MRI
• Biopsy
• All of the above

Median Overall Survival in GBM patients is-

• 4-5 months
• 8-10 months
• 12-18 months
• 20-22 months

Temozolomide can be given up to 1 year

• True
• false

The tumor marker/s having predictive or prognostic role in High Grade Glioma management is/are

• MGMT Methylation
• IDH Mutation
• 1p19qdeletion
• All of the above

Preferred choice of treatment in recurrent GBM

• Bevacizumab
• Carmustine
• Lomustine
• Only Radiotherapy

Temozolomide cannot be given in rGBM patients, if it has already been given in 1st line setting

• True
• false

Dose of Bevacizumab in rGBM

• 10mg/kg/2 weeks
• 15 mg/kg/3 weeks
• Both a and b
• None of the above

Bevacizumb is not preferred much in clinical practice as it only improves PFS and not OS

• True
• false