Module 4 Part 2: Hematology

A patient takes longer than average to stop bleeding after a blood draw. The patient has the following labs.
     PT = Normal
     aPTT = High
     BT = High
     PLT = Normal
What is the diagnosis?

• Hemophilia A
• Von Willebrand Disease
• Thrombocytopenia
• Disseminated Intravascular Coagulation

A patient has a high PT, high aPTT, high BT, and low PLT. What is the most likely diagnosis?

• Hemophilia A

• Von Willebrand Disease

• Thrombocytopenia

• Disseminated Intravascular Coagulation

A patient has a high aPTT, but normal PT, BT, and PLT. What is the most likely diagnosis?

• Hemophilia A

• Von Willebrand Disease

• Thrombocytopenia

• Disseminated Intravascular Coagulation

aPTT is elevated in von Willebrand's Disease ___ of the time

• 25%

• 50%

• 75%

• 100%

Liver disease would cause elevations in

• PT only

• aPTT only

• PT and aPTT

• PT, aPTT, BT

Hypocalcemia would affect

• Intrinsic pathway only

• Extrinsic pathway only

• Common pathway only

• All three pathways

John Doe, a 28-year-old male engineer, presented to the Hematology Clinic with a history of recurrent episodes of uncontrolled bleeding. He reported multiple instances of prolonged bleeding following minor injuries, dental extractions, and spontaneous nosebleeds since childhood. His family history was significant for a maternal uncle who had similar bleeding tendencies. John sought medical attention due to increasing concerns about the frequency and severity of his bleeding episodes. John's family history revealed a strong predisposition to bleeding disorders. His maternal uncle had a confirmed diagnosis of hemophilia B, and there were anecdotal reports of other male relatives experiencing excessive bleeding after minor injuries. How would you treat John's condition?

• Administer clotting factor VIII

• Perform a blood transfusion
• Administer clotting factor IX
• Recommend a high protein diet

Hemophilia A is treated with ___ and Hemophilia B is treated with ___

• Factor VIII and Factor IX
• Factor IX and Factor VIII
• Factor VII and Factor X
• Factor X and Factor VII

Tissue Plasminogen Activator (tPA) initiates the conversion of ___ to ___

• plasminogen to plasmin
• fibrinogen to fibrin
• prothrombin to thrombin
• angiotensinogen to angiotensin

D-dimer test can be used for which of the following conditions?

• DIC

• DVT

• PE

• Stroke