Mechanisms of Action of Antibiotics

Which of the following antibiotics blocks peptidoglycan synthesis?

• Rifampin

• Tetracycline

• Ciprofloxacin

• Penicillin

Antibiotics are used to treat infections by ___.

• viruses

• bacteria

• bacteriophages

• fungi and mold

Which types of antibiotics work by using Beta Lactam Rings?

• Streptomycin, Gentamycin, Tobramycin

• Ciprofloxacin, Rifampin

• Penicillin, Cephalosporins, Carbapenems

• Sulfonamides, Trimethoprim

Identify the Mechanism of action when

the target of the antibiotic is DNA gyrase and/or RNA polymerase.

• Interfere with metabolic pathways

• Inhibit nucleic acid synthesis

• Inhibit cell wall synthesis

• Inhibit protein synthesis

If an antibiotic binds to the ribosomes inside of the host cell, it will prevent translation. Which Mechanism of action works in this way?

• Inhibits protein synthesis

• Inhibits cell wall synthesis

• Inhibits nucleic acid synthesis

• Interferes with cell membrane

Which describes how competitive inhibition works in an antibiotic?

• The antibiotic prevents translation.

• An enzyme crucial to the bacterial cell binds to the antibiotic instead of the regular reactant (substrate).

• The antibiotic interferes with the host cell membrane and causes the cell to lyse then die.

• Competitive inhibition occurs when a molecule enhances the activity of an enzyme by binding to the reactant (substrate).

Identify the antibiotics that interfere with the host cell membrane. (More than one answer)

• Daptomycin

• Tetracycline

• Polymyxin B

• Sulfonamides

Which Mechanism of action of antibiotics is most dangerous to take internally?

• Inhibits protein synthesis.

• Interferes with metabolic pathways.

• Interferes with cell membranes.

• Inhibits nucleic acid synthesis.

Bacteria that produce Beta lactamase are resistant to which type of antibiotic?

• Tetracycline

• Penicillin

• Rifampin

• Polymyxin B