Unit 3 Cancer Biology Final Review

What will happen to this cell if p53 is activated?

• the cell will divide

• the cell will grow

• the cell will be killed off

• p53 does not affect the cell

What type of gene is p53?

• telomerase gene

• tumor suppressor gene

• stability gene

• proto-oncogene

What would happen to the cell if Notch 1 were inactivated?

• the cell will die

• the cell will survive and divide

• the cell will stop dividing

• there will be no change to the cell

Tags

NGSS.HS-LS1-4

The Ras-Raf pathway pictured is overactive/over stimulated. It must be the product of what type of gene?

• proto-oncogene

• stability gene

• tumor suppressor gene

• oncogene

Oncogenes result in which of the following outcomes?

• cell cycle arrest, apoptosis and survival

• DNA repair, cell cycle acceleration and survival

• accelerated cell growth, cell cycle arrest and survival

• accelerated cell growth, increased cell division and survival

Stability genes ensure that

• a cell with damaged DNA is killed off

• damaged DNA is removed

• damaged DNA is preserved

• damaged DNA is repaired

What would be the effect on the pathway if levels of PTEN were increased.

• no change in cellular responses

• increased cellular responses

• decreased cellular responses

• increased apoptosis

Use evidence from the pathway to identify which type of gene codes for BRCA1?

• stability gene

• onocgene

• tumor suppressor gene

• apoptosis gene

Tags

NGSS.HS-LS1-1

If cancerous cells travel throughout your body, the cells have gone through a process known as:

• Metastisize

• Migration

• Flowing

• Locomotion

Cancer is best and fully described by ...

• Uncontrolled cell growth
• Cells which grow abnormally and no longer function correctly
• Cells which have lost the ability to reproduce
• Cells which create abnormal tissues