Understanding Duchenne Muscular Dystrophy

What type of genetic mutation commonly leads to Duchenne Muscular Dystrophy (DMD)?

• Duplication of a segment of the dystrophin gene

• Deletion of a segment of the dystrophin gene

• Point mutation in the dystrophin gene

• Inversion of a segment of the dystrophin gene

Tags

NGSS.HS-LS3-2

Which protein is primarily affected by the genetic mutation in Duchenne Muscular Dystrophy?

• Myosin

• Actin

• Dystrophin

• Collagen

Tags

NGSS.HS-LS1-1

NGSS.HS-LS3-1

NGSS.HS-LS3-2

What is one of the earliest noticeable symptoms of Duchenne Muscular Dystrophy in children?

• Frequent headaches

• Difficulty with fine motor skills

• Gower's sign

• Skin rash

How does Duchenne Muscular Dystrophy primarily impact the muscles?

• Increases muscle mass

• Causes intermittent muscle spasms

• Leads to progressive muscle weakness

• Improves muscle endurance

Tags

NGSS.HS-LS3-2

Which of the following is NOT a treatment option for Duchenne Muscular Dystrophy?

• Corticosteroids

• Gene therapy

• Physical therapy

• Antibiotics

What is the role of corticosteroids in the treatment of Duchenne Muscular Dystrophy?

• They help build muscle mass

• They slow the progression of muscle weakness

• They cure the underlying genetic mutation

• They provide temporary relief from muscle pain

Which of the following is a potential future treatment under investigation for Duchenne Muscular Dystrophy?

• Over-the-counter pain relievers

• Exon skipping therapy

• High-intensity interval training

• Dietary supplements

At what age do symptoms of Duchenne Muscular Dystrophy typically begin to appear?

• Infancy

• Early childhood, between ages 2 and 5

• Adolescence

• Early adulthood

Which of the following is a common complication associated with Duchenne Muscular Dystrophy?

• High blood pressure

• Diabetes

• Cardiomyopathy

• Asthma

Tags

NGSS.HS-LS3-2

What is the typical life expectancy for individuals with Duchenne Muscular Dystrophy?

• Normal life expectancy with treatment

• Into the late 20s or early 30s with optimal care

• Into the 50s with advanced therapies

• Into the 60s with no complications