Medicinal Biochemistry- Beta oxidation of fatty acids & Diabetes

Diabetes is a

• Carbohydrate metabolic disorder

• Protein metabolic disorder

• Amino acid metabolic disorder

• Lipid metabolic disorder

Diabetes is due to

• Insufficient insulin

• Inefficient insulin

• Both A & B

• Non of the above

A: Fatty acid oxidation is also called as Beta-oxidation of fatty acid.

R: As most of the saturated fatty acids follow Beta oxidation process.

• A & R are correct and correct explanation

• A & R are correct but not correct explanation.

• A is correct

  R is incorrect

• A & R are incorrect

Stages of beta oxidation Location

1. 1. Activation a. Mitocondrial matrix

2. 2. Transport b. cytoplasam

3. 3. Beta oxidation proper c. From cytoplasam to mitrochondrial matrix

• B,

  C

  A

• A

  B

  C

• C

  B

  A

• A

  C

  B

what are the three requirements for the activation of fatty acids

• ATP

• Mg2+

• Coenzyme A

• All the above

Which of the following is a flavoenzyme

• CAT-I

• Thiokinase

• AcylCoA Dehydrogenase

• Thiolase

What are the enzymes included in transport process of activated fatty acid

• CAT-I

• CAT-II

• Both A & B

• None of the above

How many cycles of Beta oxidation proper happens for complete oxidation of 16 C Fatty acid

• 7

• 8

• 9

• 10

How many acetyl CoA is liberated for 16c fatty acid

• 6

• 7

• 8

• 9

Net ATP generated while complete oxidation of Palmityl CoA is

• 130

• 131

• 129

• 128