Science Quiz

What is AIVIA from LEICA?

• underlying principle of leica microscopy

• ALL INDIA imaging platform initiated by Indian government

• artifical intelligence based ITC instrument

• artificial intelligence based image analysis software

What is super resolution imaging ?

• biological imaging below diffraction limit of light

• biological imaging at infrared range

• biological imaging in the visible range

• biological imaging at wide range of wavelengths

Till what atomic resolution can be achieved via cryo-EM technique?

• ~2 Angstrom

• ~10 Angstrom

• it just give fuzzy images

• it can detect all atomic details

What is the resolution achieved via STED microscopy?

• greater than 250 nm

• micrometer range

• around 50 nm

• 50-100 picometer

What is the use of STED microscopy ?

• live cell imaging

• flouroscence imaging

• super resolution imaging

• all of the above

Cryo-EM technique is obviously better for larger molecules, does it also have a lower limit?

• Yes, few amino acid peptides

• Yes, ~1000 kDa

• Yes, ~50 kDa

• No lower limit

What is the typical quantum efficiency of GaAsP PMT detectors?

• 10-20%

• 30-45%

• all ranges

• none of the above

Which are the critical parameters to establish protein stability?

• IC50, aggregation, poly dispersity index

• melting temperature, aggregation, poly dispersity index

• molecular weight, melting temperature, aggregation

• all of the above

What is FLIM-FRET used for?

• measure LLPS dynamics

• measure cell cycle lifetime

• detect association lifetime of two biological molecules

• none of the above

What is the resolution of monolith?

• picomolar to milimolar

• picometer to milimeter

• piconewton to milinewton

• no question of resolution, its a hollywood movie in 2016.