Central Nervous System Nuclear Medicine

Which PET radiopharmaceutical is commonly used to study brain metabolism?

• 18F-FDG

• 99mTc-ethylene L-cysteinate dimer (ECD)

• 99mTc-pertechnetate

• 68Ga citrate

Imaging of CSF dynamics include all of the following EXCEPT:

• cisternogram

• shunt evaluation

• detection of CSF leaks

• ventriculogram

Which is the only FDA radiopharmaceutical approved for assessment of CSF dynamics?

• 99mTc-ECD

• 111In-DTPA

• 201Tl

• 18F-FDG

Perfusion agents that do not cross the BBB and are used in Brain death:

• 99mTc-diethylenetriamine pentaacetic acid (DTPA) and 99mTc-HMPAO

• 99mTc-HMPAO and 99mTc-pertechnetate

• 99mTc-DTPA and 99mTc-pertechnetate

• 99mTc-ethylene L-cysteinate dimer (ECD) and 99mTc-HMPAO

Which radiopharmaceutical is commonly used for imaging of brain tumors?

• 111In-DTPA

• 18F-FDG

• 99mTc-HMPAO

• 18F Amyvid

The most sensitive, effective & practical imaging technique for localizing an epileptogenic focus:

• ictal SPECT

• interictal SPECT

• ictal PET

• interictal PET

What type of compounds are unable to cross the blood brain barrier without active transport?

• Lipophilic

• Oxygen

• Carbon dioxide

• Lipophobic

All of the following are radiopharmaceuticals that could be used in a brain death EXCEPT:

• 18F-FDG

• 99mTc-HMPAO

• 99mTc-ECD

• 99mTc-DTPA

The intrathecal injection for CSF imaging allows for the dose to be administered:

• during a seizure

• into the subdural space

• into the subarachnoid space

• into the spinal cord

All of the following are true about FDG use in brain imaging, EXCEPT:

• normal cerebral and cerebellar neurons use FDG avidly

• FDG accumulation is comparable to that of normal cortical gray matter

• primary brain tumors and mets are easily demonstrated on FDG PET

• primary and metastatic brain tumors are missed on FDG PET scans