Lecture 8 MHC

Interaction of T cells with a peptide requires which of the following? (Select all that apply)

• T cell receptor

• peptide

• MHC molecule

• CD4/CD8 co receptor

Helper T cells are _________ restricted (Can only interact with peptides presented by that MHC class molecule)

• MHC class 1

• MHC class 2

All nucleated cells express MHC class I

• True

• False

In theory, any cell expressing MHC class I can present an MHC/peptide complex to a cytotoxic T cell

• True

• False

Which of the following cells express both MHC class 1 and 2?

• B cells

• neutrophils

• macrophages

• dendritic cells

A cell can only express one MHC class isotype

• True

• False

A bone marrow transplant may not be appropriate from a given donor (Jane) to a given recipient (Jane's cousin Bob), even though Jane has previously given blood for one of Bob's needed transfusions.

• True

• False

Tags

NGSS.HS-LS3-1

NGSS.HS-LS3-2

You mate two inbred (both haplotypes are identical within each animal) mouse strains. Can the offspring received a skin graft from mom and/or dad?

• Yes

• No