Neurogenesis

What is the initial structure that develops into the mature central nervous system (CNS)?

• Neural plate

• Neuroepithelial cells

• Ventricular zone

• Dorsal root ganglia

During neurogenesis, what do neuroepithelial cells differentiate into?

• Neurons and glia

• Neural plate

• Ventricular zone

• Dorsal root ganglia

What happens to the ventricular zone during the development of the nervous system?

• It gradually depletes

• It expands

• It remains unchanged

• It becomes the neural plate

What is the origin of the neural tube?

• Mesoderm

• Endoderm

• Ectoderm

• Hypoderm

What type of polarity do epithelia possess?

• Lateral-medial

• Apical-basal

• Dorsal-ventral

• Anterior-posterior

During neurulation, how does the orientation move?

• Medial-lateral to dorsal-ventral

• Anterior-posterior to lateral-medial

• Dorsal-ventral to medio-lateral

• Apical-basal to anterior-posterior

What is also involved in the development of the nervous system?

• Cytoplasm

• ECM (Extracellular Matrix)

• Mitochondria

• Ribosomes

What is the role of laminin in the zebrafish neural tube?

• It acts as a counter stain for nuclei.

• It is involved in apical tight junctions.

• It is part of the extracellular matrix (ECM).

• It is a marker for E-cadherin.

What does the magenta color indicate in the immunohistochemistry of the zebrafish neural tube?

• E-cadherin

• Laminin

• ZO1 – apical tight junctions

• Nuclei

What is the significance of interkinetic nuclear migration in neuroepithelial cells?

• It helps in the formation of the yolk.

• It corresponds with the cell cycle stage.

• It stabilizes the notochord.

• It prevents cell division.