Atropine is a natural alkaloid and a tertiary amine.

• True

• False

Atropine does not cross the blood-brain barrier.

• True

• False

Answer explanation

This is false because atropine, being a tertiary amine, is lipophilic and can cross the blood-brain barrier. It can exert central nervous system effects, such as causing delirium or agitation in high doses.

Atropine is used to treat sinus bradycardia.

• True

• False

Scopolamine penetrates into the brain more readily compared to atropine.

• True

• False

Scopolamine is effective in preventing nausea and vomiting in motion sickness.

• True

• False

Scopolamine butylbromide has significant central nervous system effects.

• True

• False

Answer explanation

This is false because scopolamine butylbromide is a quaternary ammonium compound, which reduces its ability to cross the blood-brain barrier. As a result, it has minimal or no central nervous system effects.

Ipratropium is a short-acting muscarinic antagonist used for asthma treatment.

• True

• False

Tiotropium is a long-acting muscarinic antagonist used to treat chronic bronchitis and emphysema.

• True

• False

Cyclopentolate is used to produce miosis for diagnostic purposes.

• True

• False

Answer explanation

This is false because cyclopentolate is used to induce mydriasis (pupil dilation) and cycloplegia (paralysis of the ciliary muscle) for diagnostic purposes, not miosis (pupil constriction).

Pirenzepine is an M1 selective antagonist used for peptic ulcer disease.

• True

• False