Quick 10Q: Krebs Cycle

Front

Where does the Krebs cycle take place?

Back

The Krebs cycle takes place in the mitochondrial matrix.

Front

How does the Krebs cycle allow for ATP synthesis?

Back

The Krebs cycle allows for ATP synthesis by storing high energy electrons in NADH and FADH2, which shuttle to the electron transport chain (ETC) to generate a proton gradient.

Front

What percentage of glucose is left after the Krebs cycle?

Back

0% of glucose is left after the Krebs cycle.

Front

What is the effect of an inhibitor that stops the oxidation of NADH or FADH2?

Back

It decreases cellular respiration and results in less ATP being synthesized.

Front

What is the difference between NADH and FADH2?

Back

NADH holds higher energy electrons compared to FADH2, and NADH is produced during glycolysis while FADH2 is produced in the Krebs cycle.

Front

What is the main purpose of the Krebs cycle?

Back

The main purpose of the Krebs cycle is to break down glucose and other substrates to produce energy carriers (NADH and FADH2) for ATP synthesis.

Front

What are the main products of one turn of the Krebs cycle?

Back

One turn of the Krebs cycle produces 3 NADH, 1 FADH2, 1 ATP (or GTP), and 2 CO2.

Front

How many times does the Krebs cycle turn for each glucose molecule?

Back

The Krebs cycle turns twice for each glucose molecule, as one glucose molecule is split into two pyruvate molecules.

Front

What role does coenzyme A play in the Krebs cycle?

Back

Coenzyme A is essential for the formation of acetyl-CoA, which enters the Krebs cycle.

Front

What is substrate-level phosphorylation?

Back

Substrate-level phosphorylation is a method of generating ATP by transferring a phosphate group from a substrate directly to ADP.