Cancer: Clues from Cell Biology CfU s21

Front

What is the genetic stability of cancer cells?

Back

Cancer cells are not genetically stable; they often have rearrangements, duplications, and deletions of their chromosomes.

Front

How many genetic changes are typically observed in cancer cells?

Back

More than one genetic change is usually observed in cancer cells.

Front

What role do cancer stem cells play in cancer?

Back

Cancer stem cells may contribute to the formation, recurrence, and metastasis of various cancer types and are potential targets for treatment.

Front

What does it indicate if all cells in a tumor have the same inactivated X-chromosome?

Back

It suggests a common origin for the tumor, indicating that it may have arisen from a single cell.

Front

What is the model of cancer initiation involving carcinogens?

Back

Carcinogens induce mutations in critical genes, leading to abnormal growth in the affected cell and its offspring.

Front

Define carcinogen.

Back

A carcinogen is any substance that promotes the formation of cancer.

Front

What is a mutation?

Back

A mutation is a change in the DNA sequence that can lead to changes in gene function.

Front

What is metastasis in cancer?

Back

Metastasis is the spread of cancer cells from the original tumor to other parts of the body.

Front

What is the significance of genetic changes in cancer development?

Back

Genetic changes can lead to uncontrolled cell growth and the development of tumors.

Front

What are solid tumors?

Back

Solid tumors are masses of tissue that can form in various organs, as opposed to blood cancers like leukemia.