Mutation and Cancer

Once a mutation has occurred, it is definitely going to be permanent in the organism.

• True
• False

Tags

NGSS.HS-LS3-2

A nonsense mutation results in _________.

• A truncated protein
• A slightly altered polypeptide chain
• A shift in the reading frame
• The regulatory sequence being altered.

Tags

NGSS.HS-LS3-2

What type of gene do cancer researchers often "turn off" in order to study cancer?

• proto-oncogense
• oncogenes
• constitutive genes
• tumor supressor genes

Because some amino acids can be coded for by multiple codons, this type of mutation is possible.

• Nonsense Mutation
• Missense Mutation
• Degenerate Mutation
• Silent Mutation

Tags

NGSS.HS-LS3-2

If below is the wild-type DNA sequence, which one shows a point mutation?
5'-ATTCGC-3'

• 5' - AATTCGC - 3'
• 5'- ATCCGC - 3'
• 5' - ATCGC - 3'
• 5' - ATTCGC - 3'

Tags

NGSS.HS-LS3-2

A base pair substitution can result in all of the following except __________.

• Missense mutation
• Frameshift Mutation
• Silent Mutation
• Nonsense mutation

Tags

NGSS.HS-LS3-2

What kind of mutation is the result of an insertion?

• Silent Mutation
• Missense mutation
• Nonsense mutation
• Frameshift mutation

If a nonsense mutation occurred in the gene for the lac repressor, how would it affect the lac operon?

• The lac operon would be on all the time
• The lac operon would be off all the time
• There would be no change in the expression of the lac operon because the repressor does not affect the operon itself.
• It would depend on the presence of glucose.

Tags

NGSS.HS-LS3-2

Which of these are not changes to a proto-oncogene that would contribute to the development of cancer?

• retroviral insertions
• apoptosis
• missense mutations
• chromosomal translocation

Mutations usually _____________

• Are helpful
• Are harmful
• Are awesome
• happen spontaneously

Tags

NGSS.HS-LS3-2