Nucleophiles and electrophiles
Chemistry
University
NGSS covered
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This quiz focuses on nucleophiles and electrophiles, fundamental concepts in organic chemistry that form the backbone of reaction mechanism understanding. The material is appropriate for grade 12 or college-level chemistry students who are studying organic reaction mechanisms and Lewis acid-base theory. Students need to master the definitions and characteristics of nucleophiles as electron pair donors (Lewis bases) and electrophiles as electron pair acceptors (Lewis acids), while understanding how molecular structure determines reactivity. The questions require students to analyze molecular structures, identify electron-rich and electron-poor species, recognize the role of formal charges and lone pairs, and apply these concepts to predict which molecules can act as nucleophiles or electrophiles in chemical reactions. This quiz was created by a classroom teacher who designed it for students studying organic chemistry at the high school or introductory college level. The assessment serves as an excellent formative evaluation tool to gauge student comprehension before moving into more complex reaction mechanisms, and it works effectively as a warm-up activity to activate prior knowledge or as homework to reinforce classroom instruction. Teachers can use this quiz to identify misconceptions about Lewis acid-base theory and to ensure students have the foundational knowledge necessary for understanding substitution and addition reactions. The content aligns with NGSS HS-PS1-2 regarding chemical bonding and molecular interactions, as well as college-level organic chemistry standards that emphasize mechanistic thinking and structure-reactivity relationships.
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7 questions
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1.
MULTIPLE CHOICE QUESTION
1 min • 1 pt
Which of the following is NOT true about nucleophiles?
donates an electron pair to an electrophile to form a chemical bond
all molecules or ions with a free pair of electrons or at least one pi bond can act as nucleophiles
nucleophile are Lewis acids by definition
a nucleophile becomes attracted to a full or partial positive charge
2.
MULTIPLE CHOICE QUESTION
1 min • 1 pt
Which of the following statement is INCORRECT about electrophiles?
Electrophiles are positively charged or neutral species having vacant orbitals
The electrophiles are attacked by the most electron-populated part of one nucleophile
Electrophiles are Lewis base
3.
MULTIPLE CHOICE QUESTION
30 sec • 1 pt
Which of the following cannot react as a nucleophile?
CH3NH2
(CH3)2NH
(CH3)3N
(CH3)4N+
Tags
NGSS.HS-PS1-1
NGSS.HS-PS1-2
4.
MULTIPLE CHOICE QUESTION
30 sec • 1 pt
Select the nucleophile
CH3+
HCl
I-
CO2
Tags
NGSS.HS-PS1-1
NGSS.HS-PS1-2
5.
MULTIPLE CHOICE QUESTION
30 sec • 1 pt
Select the electrophile
CH3+
Ne
Cl-
CO2
Tags
NGSS.HS-PS1-1
NGSS.HS-PS1-2
6.
MULTIPLE CHOICE QUESTION
30 sec • 1 pt
Select the electrophile
CH3-
BH3
NH3
H2
Tags
NGSS.HS-PS1-1
NGSS.HS-PS1-2
7.
MULTIPLE CHOICE QUESTION
30 sec • 1 pt
Select the nucleophile
CH3CH3
BH3
NH3
H2
Tags
NGSS.HS-PS1-1
NGSS.HS-PS1-2
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