Mutations and Genetic Disorders

Which of the following applies to GERM-LINE MUTATIONS

• They are only found in some body cells

• They are found in gametes

• They can be inherited or passed on

• They are not inherited or passed on

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The bottom DNA sequence in the image has been altered by this type of mutation

• substitution

• insertion

• deletion

• translocation

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Which of the following applies to SOMATIC MUTATIONS

• They are only found in some body cells

• They are found in all body cells

• They are inherited or passed on

• They are not inherited or passed on

An inherited disorder that causes a buildup of amino acids

• Phenylketonuria (PKU)

• Spina Bifida

• Down syndrome

• Huntingtons disease

Answer explanation

Effects: if undetected may cause permanent internal damage & cognitive disability

Treatment: modified diet

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A condition in which red blood cells are not shaped as they should be

• Cystic fibrosis

• Sickle cell Anemia

• Spina Bifida

• Tay-Sachs Disease

Answer explanation

Effects: chronic illness to early death

Treatment: blood transfusion, proper medication

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Caused by an extra chromosome

• Sickle cell Amelia

• Down syndrome

• Huntington’s disease

• Fragile x syndrome

Answer explanation

effects: delayed language development, severe cognitive disability

treatment: maybe surgery, specialized learning programs

An inherited disease in which the body makes very thick, sticky mucus

• cystic fibrosis

• Spina Bifida

• Tays-Sach Disease

• Down syndrome

Answer explanation

Effects: causes issues in digestive,reproductive,respiratory

Treatment: exercise, dietary supplements

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What's the sneaky culprit behind a genetic disorder, according to our story featuring KloSay and MayHtoo?

• Being a solo artist with only one copy of a gene

• Munching on faulty proteins

• A sneaky mutation in a gene that's supposed to be coding for proteins

• Going overboard and building a protein empire

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Pop Quiz! Which of these is NOT a real mutation type we've talked about in KloSay's genetics class?

• Transcript

• Missense

• Nonsense

• Frameshift

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Imagine KloSay and Aurore are genetic engineers! What happens when a frameshift mutation sneaks into their work?

• It throws a surprise party, stopping protein production in its tracks!

• It's like adding an unexpected twist, inserting a small part into the protein.

• It plays the role of a thief, removing a part of the protein.

• It's the ultimate prankster, distorting the entire assembly instruction!

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