MI 3.1.4 & 3.1.5 Microarrays

What does BLACK indicate in dna microarray?

• gene expression in cancer cells

• gene expression in healthy and cancer cells

• no gene expression

• gene expression in healthy cells

When comparing healthy and cancerous lung cells on a microarray, what color would you expect the dot that represents the gene for producing melanin (pigment for skin color)?

• Red

• Yellow

• Green

• Black

Which genes are expressed in both normal and in cancerous cells?

• Genes marked by red spots only

• Genes marked by red and green spots

• Genes marked by black and yellow spots

• Genes marked by yellow spots only

In the microarray, what does the RED color indicate?

• these genes are not expressed or turned off

• these genes are expressed or turned on in cancer

• these genes are expressed in healthy cells

• there are no genes in this cell

What is the strength and direction of correlation between two variables having a correlation coefficient value of 0.67?

• a. perfect negative correlation

• b. weak positive correlation

• c. very weak positive correlation

• d. strong positive correlation

What is the name of the type of diagram shown?

What happens after the DNA from the sample is applied to the DNA microarray?

• the mRNA falls off the spot

• the DNA comes apart

• the tRNA will join the complementary strand

• the cDNA will hybridize with the single stranded DNA molecules on the microarray

Which unknown gene sequences might belong to cancer-suppressor genes?

• Genes marked by red spots

• Genes marked by green spots

• Genes marked by black spots

• Genes marked by yellow spots

Which two genes shown have the highest similarity after calculating correlation coefficient data?

• C and A

• B and D

• D and A

• B and C

What is transcribed from DNA to produce a protein and is a good indication of whether or not a particular gene is expressed?

• mRNA

• cDNA

• tRNA

• trRNA