NMRR and MREC

What does NMRR stand for?

• National Medical Registration and Research

• National Medical Research Register

• National Medical Research Repository

• National Medical Review and Registration

Who is responsible for submitting a research project to NMRR?

• Local Clinical Research Centre office

• Only the hospital director

• The Principal Investigator (PI) or designated team member

• The Ministry of Health (MOH)

What is the primary purpose of NMRR?

• To track patient medical records

• To facilitate research registration and ethical approval in Malaysia

• To store laboratory test results

• To approve all clinical trials automatically

Why is the IA-HOD-IA Form required for NMRR submission?

• It confirms the institution’s awareness and approval of the investigator involvement in the research

• It replaces the need for MREC ethics approval

• It ensures funding is allocated for the research

• It is only needed for multi-center studies

What is the first step in the NMRR submission process?

• Obtaining institutional approval

• Registering as a user on the NMRR portal

• Uploading all required documents

• Receiving ethics approval

How can a researcher track the status of their NMRR submission?

• By calling the NMRR office directly

• Through the submission tracking feature in the NMRR portal

• By emailing the ethics committee weekly

• By waiting for call from local CRC office

Which committee is responsible for reviewing the ethical aspects of a research submission in NMRR?

• Ministry of Health Malaysia

• Medical Research & Ethics Committee (MREC)

• National Pharmaceutical Regulatory Agency (NPRA)

• Research Management Centre (RMC)

What is the significance of MREC approval in the NMRR process?

• It allows researchers to bypass institutional approval

• It grants ethical clearance for the research to proceed

• It serves as a funding approval document

• It is only required for animal studies

Dr. X has submitted her research proposal to NMRR and is waiting for MREC approval. However, she wants to start collecting data early to save time. What should she do?

• Begin data collection to save time

• Wait for approval from MREC before starting data collection.

• Collect data and submit it to NMRR later for record purposes.

• Submit a request for expedited approval so she can start immediately.

Dr. K research initially involved surveys, but he later decides to conduct interviews instead. He does not update his NMRR submission or inform MREC. What is the consequence of this action?

• His study remains valid since the core topic is unchanged.

• This is considered an ethics violation because significant study changes must be reported.

• He only needs to notify his institution, not MREC.

• He can proceed with data collection as long as he informs participants