Dystrophin and Muscle Function Quiz

Which statement best describes the impact of non-functional dystrophin protein in Duchenne Muscular Dystrophy?

• It causes excessive muscle growth

• It leads to inflammation in the joints

• It results in muscle fiber damage and weakness

• It increases muscle protein synthesis

In healthy muscle tissue, where is dystrophin protein primarily located?

• Inside the muscle nucleus

• Within blood vessels

• In the myosin

• Along the muscle cell membrane

What is a characteristic structural feature of skeletal muscle tissue?

• Smooth, non-striated (non-striped) appearance

• Striated (striped), cylindrical appearance

• Single nucleus in the center

• Lack of organized filaments

Which process is directly affected by the absence of functional dystrophin in muscle cells?

• Oxygen transport to muscles

• Hormone production

• Structural stability during contraction

• Blood flow regulation

Why are creatine kinase (CK) levels typically elevated in Duchenne Muscular Dystrophy patients?

• Due to increased muscle building

• Because of enhanced protein synthesis

• Due to muscle cell damage and protein leakage

• Because of improved muscle metabolism

What role does abnormal calcium regulation play in DMD muscle cells?

• It increases muscle strength

• It promotes muscle repair

• It helps with protein synthesis

• It contributes to muscle cell death

Which statement best describes the relationship between dystrophin deficiency and calcium levels in DMD?

• Dystrophin deficiency leads to decreased calcium levels

• Calcium levels remain unchanged despite dystrophin deficiency

• Dystrophin deficiency results in excessive calcium entry into cells

• Calcium levels are only affected in cardiac muscle

Tags

NGSS.HS-LS1-3

How are creatine kinase levels used in DMD diagnosis?

• They indicate the patient's age

• They serve as an early diagnostic marker

• They predict life expectancy

• They determine treatment effectiveness only

What is the role of dystrophin in muscle cells?

• It provides energy to muscle cells.

• It helps in muscle contraction.

• It stabilises muscle cell membranes.

• It transports oxygen to muscles.

Answer explanation

Dystrophin is crucial for stabilising muscle cell membranes by linking the cytoskeleton to the extracellular matrix. This function helps protect muscle cells from damage during contraction, making it the correct choice.

explanation for how muscles contract to produce force

• expansion contraction theory

• sliding filament theory

• muscular contraction theory

• evolution