Lipid Mobilization and Catabolism Quiz

What is the primary function of hormone-sensitive lipase (HSL) in adipose tissue?

• To synthesize triglycerides

• To hydrolyze triglycerides

• To convert glycerol to glucose

• To transport fatty acids

Which hormone activates hormone-sensitive lipase (HSL)?

• Insulin

• Glucagon

• Epinephrine

• Cortisol

What is the fate of glycerol released from triglyceride hydrolysis?

• It is stored in adipose tissue

• It is converted to dihydroxyacetone phosphate for gluconeogenesis

• It is used for fatty acid synthesis

• It is converted to glucose

Which of the following fatty acids can diffuse freely into mitochondria?

• Short-chain fatty acids

• Very long-chain fatty acids

• Medium-chain fatty acids

• Long-chain fatty acids

What is the role of carnitine acyltransferase-1 in fatty acid metabolism?

• Converts acetyl-CoA to glucose

• Activates fatty acids

• Inhibits β-oxidation

• Transfers fatty acyl groups to carnitine

What is the primary product of β-oxidation of palmitate (16:0)?

• 6 Acetyl-CoA

• 8 Acetyl-CoA

• 2 Acetyl-CoA

• 4 Acetyl-CoA

Which enzyme is inhibited by malonyl-CoA?

• Acetyl-CoA carboxylase

• HMG-CoA lyase

• Carnitine acyltransferase-1

• Fatty acyl-CoA synthetase

What is the primary treatment for MCAD deficiency?

• Frequent feeding

• High-fat diet

• Intravenous glucose

• Low-carbohydrate diet

What is the main consequence of MCAD deficiency during fasting?

• Increased glucose production

• Profound hypoglycemia

• Increased ketone production

• Elevated triglycerides

Which vitamin is required for the enzyme methylmalonyl-CoA mutase?

• Vitamin B12

• Vitamin B6

• Vitamin C

• Vitamin A