Personalized Therapeutics: Final: Fancherish

What are the side effects expected with ketogenic diet?

• hypoglycemia

• constipation

• kidney stones

• osteoporosis & osteopenia

• dyslipidemia

Which of the following are ketogenic excipients?

• cellulose

• polyethylene glycol

• acesfulame

• starch

• sucrose

Answer explanation

Ketogenic Excipients (Good)

1.     Cellulosic Polymers (Cellulose, hypromellose)

2.     Artificial Sweeteners (Acesfulame K, aspartame, sucralose, saccharin, stevia)

3.     Co-solvents (Water, polyethylene glycol, ethanol)

Anti-ketogenic (Bad)

1.     Starches

2.     Sugar alcohols (Glycerin, ending in “tol”, ending in “lol”)

3.     Organic Acids (Ascorbic acid, lactic acid, citric acid)

4.     Sugars (“ose” gals, sucrose, corn syrup)

Which of the following are anti-ketogenic?

• lactic acid

• polyethylene glycol

• acesfulame

• starch

• sucrose

Answer explanation

Ketogenic Excipients (Good)

1.     Cellulosic Polymers (Cellulose, hypromellose)

2.     Artificial Sweeteners (Acesfulame K, aspartame, sucralose, saccharin, stevia)

3.     Co-solvents (Water, polyethylene glycol, ethanol)

Anti-ketogenic (Bad)

1.     Starches

2.     Sugar alcohols (Glycerin, ending in “tol”, ending in “lol”)

3.     Organic Acids (Ascorbic acid, lactic acid, citric acid)

4.     Sugars (“ose” gals, sucrose, corn syrup)

Genetic information nondiscrimation act (GINA)

• was enacted in 2008 and protects individuals from discrimination in both employment and health insurance

• allows insurers to vary premiums based on only certain key characteristics

• precludes from charging premiums (more)

• prohibits excluding coverage for preexisting health conditions

Patient Protection and Affordable Care Act

• was enacted in 2008 and protects individuals from discrimination in both employment and health insurance

• allows insurers to vary premiums based on only certain key characteristics

• precludes from charging premiums (more)

• prohibits excluding coverage for preexisting health conditions

Risks associated with strong genetic information in the EHR:

• increased accessibility by increased number of HC workers

• inadvertent disclosure

• increase accessibility by insurers

• disclosure of genetic results without proper education

• gain of privacy

Answer explanation

Risks associated with strong genetic information in the EHR:

o   Loss of privacy

o   Inc. Accessibility by inc. # of HC workers

o   Inadvertent disclosure

o   Inc. Accessibility by insurers

o   Disclosure of genetic results w/o proper education