
HIV Pathology Part 2
Authored by Terry Robinson
Other
University
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45 questions
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1.
MULTIPLE CHOICE QUESTION
30 sec • 1 pt
What is the primary mechanism of action of NNRTIs?
Mimic nucleosides to terminate DNA chains
Inhibit protease cleavage of viral proteins
Bind directly to reverse transcriptase at a non-active site
Block viral entry into host cells
2.
MULTIPLE CHOICE QUESTION
30 sec • 1 pt
Which of the following NNRTIs is known for causing vivid dreams and CNS effects?
nevirapine
efavirenz
rilpivirine
doravirine
3.
MULTIPLE CHOICE QUESTION
30 sec • 1 pt
Which of the following NNRTIs is considered a second-generation agent with improved resistance profile?
nevirapine
efavirenz
rilpivirine
zidovudine
4.
MULTIPLE CHOICE QUESTION
30 sec • 1 pt
What is a major disadvantage of NNRTIs compared to other antiretroviral classes?
poor oral bioavailability
high cost
low genetic barrier to resistence
need for boosting agents
5.
MULTIPLE CHOICE QUESTION
30 sec • 1 pt
What is a key difference between NNRTIs and NRTIs?
NNRTIs require phosphorylation for activation
NNRTIs are nucleoside analogs
NNRTIs bind directly to reverse transcriptase without mimicking nucleosides
NNRTIs inhibit integrase
6.
MULTIPLE CHOICE QUESTION
30 sec • 1 pt
Which of the following is a correct mnemonic to remember common NNRTIs?
LATE
REDEN
NAVIR
GRAVIR
7.
MULTIPLE CHOICE QUESTION
30 sec • 1 pt
Which NNRTI is known for having the fewest CNS side effects and a favorable lipid profile?
efavirenz
doravirine
nevirapine
zidovudine
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