Year 1 MBChB MSK System

Cartilage is formed of what cells?

• Chondroblasts

• Chondrocytes

• Osteocytes

• Osteoblasts

• Cartilocytes

What is the most prevalent collagen found in Fibrocartilage?

• Type I collagen

• Type II collagen

What structure connects Bone to Bone

• Tendon

• Ligament

• Artery

• Cartilage

What does the I Band contain in a myofibril?

• Only thin filaments

• Both thin and thick filaments

• The crossover between thin and thick filaments

• Only thick filaments

What is the name given to the region that spans the entire thick filament, including the overlap with thin filaments?

• H zone

• A band

• I band

• Z disk

• M line

Order the stages of the muscle contraction cycle?

• ATP is hydrolysed, myosin repositions into a high energy state

• Myosin binds to exposed actin, forming the actin-myosin bridge

• Ca2+ binds to Troponin-C, exposing Actin binding sites

• ATP binds to myosin, detaching it from actin

• Power stroke occurs

What muscle fibres are described as "slow-twitch, oxidative and fatigue resistant"?

• Type I

• Type II

Type IIb/IIx are...?

• Fast oxidative fibres, with moderate fatigue resistance

• Slow oxidative fibres, with high fatigue resistance

• Medium fibres with medium resistance

• Fast glycolytic fibres with rapid contraction and quick fatigue

What protein tags proteins for degradation?

• E1

• E2

• Ubiquitin

• Actin

• Postmitotic

Which hypertrophy increases the quantity of contractile proteins?

• Sarcoplasmic

• Myofibrilar