Gi Quiz - Round 1

Who performed the first liver biopsy ?

• Paul Ehrlich

• Charles Dotter

• Menghini

• Peter Scheurer

The arow indicates a structure within a damaged hepatocyte.

What is the pathological basis of its formation?

• Damaged cytoskeletal proteins

• Viral inclusions

• Storage of glycogen

• Alpha1 antitrypsin inclusions

In which of the following conditions is ALT typically normal or only mildly raised despite significant liver disease?

• Acute hepatitis A

• Autoimmune hepatitis

• Alcoholic cirrhosis

• Hepatitis B reactivation

A photograph of the cut surface of a liver is provided. What is the most likely underlying pathology for this appearance?

• Acute haemorrhagic necrosis

• Chronic venous congestion

• Cirrhosis

• Portal hypertension

A 45-year-old obese male with diabetes mellitus was diagnosed with MASLD with advanced fibrosis. What is the most useful antidiabetic medication for this patient?

• Pioglitazone

• Sitagliptin

• Semaglutide

• Insulin

Which of the following is NOT an indication for treatment with albumin in a patient with decompensated cirrhosis?

• Following large volume paracentesis

• Treatment of spontaneous bacterial peritonitis

• Hepatic encephalopathy

• Hepato-renal syndrome

The following treatment option has the best evidence for delaying decompensation in patients with compensated cirrhosis

• Carvedilol

• Simvastatin

• Vitamin E

• Ursodeoxycholic acid

Which of the following is the primary mechanism of lactulose in preventing hepatic encephalopathy?

• Acting as a systemic antibiotic to reduce gut bacteria

• Acidifying colonic contents to convert ammonia (NH3) to ammonium (NH4+)

• Increasing renal ammonia excretion

• Blocking ammonia production in the liver

A Hepatitis B serology profile of a patient presented with icterus is given below. Which of the following is the correct interpretation of these results?

• Early acute hepatitis B infection

• Chronic active hepatitis B infection

• Relatively recent, resolving, hepatitis B infection

• Past resolved hepatitis B infection

The parasitic stage causing this cystic lesion in the liver is

• Ascaris lumbricoides larval worm

• Echinococcus granulosus larval worm

• Entamoeba histolytica trophozoite

• Fasciola hepatica adult worm