MLT 2212 Basic Immunology Exam 3 Review Ch 14-24

Reaction to poison ivy is which type of hypersensitivity?

• I

• II

• III

• IV

Which isotype of immunoglobulin is involved in type I hypersensitivity?

• IgE

• IgA

• IgG

• IgM

Which of the following diseases is an example of type II hypersensitivity?

• Anaphylaxis

• Myasthenia gravis

• Post-streptococcal glomerulonephritis

• Bruton's agammaglobulinemia

Hypersensitivities to poison ivy and nickel are:

• mediated by IgG and IgM antibodies.

• immunodeficiency diseases.

• IgE responses to a hapten.

• macrophage and T-cell responses to a hapten.

Type I hypersensitivity involves:

• IgE binding to mast cells and basophils.

• phagocytic cell degranulation and proteolytic enzyme activity.

• a kidney membrane antigen and specific antibody.

• natural killer cell activation.

An example of a condition that involves type III hypersensitivity is:

• myasthenia gravis.

• allergic rhinitis.

• contact sensitivity.

• rheumatoid arthritis.

A hypersensitivity reaction characterized by the presence of IgG that reacts with soluble antigen best describes:

• type III hypersensitivity.

• contact dermatitis.

• type II hypersensitivity.

• asthma.

Which of the following occurs in hemolytic disease of the newborn?

• IgE builds up on the mother's cells.

• The Rh– mother is exposed to Rh+ baby cells.

• The Rh+ mother is exposed to Rh– baby cells.

• The baby must be Rh–.

A direct antiglobulin test is ordered on a patient sample. This test detects:

• in vivo attachment of antibodies to red blood cells.

• allergic reaction.

• passive agglutination.

• naturally occurring antibodies.

What is meant by “gating” in flow cytometry?

• The chromatic arrangement of cellular populations

• The process by which one cell population adheres to another population

• An electronic window separating subpopulations of cells

• An electronic device measuring all populations of cells