The high concentration of protons generated by the ETC builds up in the:

Space between the two mitochondrial membranes (intermembrane space)

ATP synthase produces ATP by using energy from:

Proton flow down its gradient through FO → F1 mechanism

Electrical signals from the nucleus

The process that couples the ETC-generated proton gradient to ATP production is called:

Substrate-level phosphorylation

Which statement is TRUE about Complex II?

It is part of the citric acid cycle enzyme complex and passes electrons from FADH2 to Q.

It pumps protons across the membrane.

It receives electrons from NADH.

If the ETC halts at one complex, what happens next?

Electron flow and proton pumping stop, reducing ATP production.

Electrons bypass the blocked complex and continue normally.

ATP production increases to compensate.

O₂ becomes the donor of electrons.

Which step produces the majority of ATP during cellular respiration?

Oxidative phosphorylation (ETC + ATP synthase)

Substrate-level phosphorylation in pyruvate processing

Water formation at the end of the ETC involves:

O₂ accepting electrons and protons to form H₂O

Ubiquinone (Q) functions primarily by:

Carrying electrons between Complex I/II and Complex III

Pumping protons across the membrane

Which statement about lateral mobility of ETC proteins is correct?

The complexes can move laterally within the inner membrane.

The complexes are fixed and never move.

The complexes move into the outer membrane for electron transfer.

The complexes move into the cytoplasm during activity.

Which description best matches oxidative phosphorylation?

Oxidation reactions that create a proton gradient and phosphorylation of ADP to ATP by ATP synthase.

Glycolytic breakdown of glucose in the cytoplasm.

Direct phosphorylation of ADP during glycolysis.

Conversion of pyruvate to lactate.

If a poison blocks Complex IV, the immediate effect is:

Electrons cannot be transferred to O₂; ETC stalls and proton pumping stops

FADH2 production increases to compensate

Glycolysis will stop immediately

Which of the following is NOT a function of the inner mitochondrial membrane?

Providing the location for ATP synthase to convert ADP→ATP

Serving as the site of glycolysis

Where in the mitochondrion would you find the citric acid cycle enzymes?

Embedded in the inner membrane facing the intermembrane space

Which statement about ATP yield is safest and most accurate given cellular respiration described here?

Most ATP is produced by oxidative phosphorylation (ETC + ATP synthase).

All ATP is produced in glycolysis.

The citric acid cycle alone produces the largest ATP amount.

ATP synthase consumes ATP instead of producing it.

Cytochrome c is best described as:

A mobile electron carrier between Complex III and Complex IV

A membrane-spanning proton pump

The enzyme that converts pyruvate to acetyl-CoA

The catalytic subunit of ATP synthase

Which two things are required for oxidative phosphorylation to proceed normally?

Absence of oxygen and high cytoplasmic ATP

Oxygen as final electron acceptor and an intact proton gradient across the inner membrane

Fermentation enzymes and excess glucose

Cellular Respiration Quiz (2)

Authored by Anoushka Mitra

Biology

University

NGSS covered

Used 1+ times

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30 questions

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MULTIPLE CHOICE QUESTION

1 min • 2 pts

Where does glycolysis occur?

Mitochondrial matrix

Intermembrane space

Nucleus

Cytoplasm

Tags

NGSS.HS-LS2-3

NGSS.HS-LS2-5

MULTIPLE CHOICE QUESTION

1 min • 2 pts

Pyruvate processing (pyruvate → acetyl-CoA) occurs in the:

Cytoplasm

Mitochondrial intermembrane space

Mitochondrial matrix

Endoplasmic reticulum

Tags

NGSS.HS-LS1-7

NGSS.HS-LS2-3

MULTIPLE CHOICE QUESTION

1 min • 2 pts

Where are the protein complexes of the electron transport chain (ETC) embedded?

Outer mitochondrial membrane

Inner mitochondrial membrane

Mitochondrial matrix

Cytoplasm

Tags

NGSS.HS-LS2-3

MULTIPLE CHOICE QUESTION

1 min • 2 pts

Which electron carrier donates electrons to Complex I?

FADH2

Q (ubiquinone)

NADH

O₂

Tags

NGSS.HS-LS1-7

MULTIPLE CHOICE QUESTION

1 min • 2 pts

Which complex is the site where O₂ accepts electrons to form water?

Complex I

Complex II

Complex III

Complex IV

Tags

NGSS.HS-LS1-7

MULTIPLE CHOICE QUESTION

1 min • 2 pts

Which complexes actively pump protons from the matrix toward the intermembrane space? (select best single answer)

I, II, III

I, III, IV

II, III, IV

I, II, IV

Tags

NGSS.HS-LS2-3

MULTIPLE CHOICE QUESTION

1 min • 2 pts

FADH2 donates electrons primarily to:

Complex I

Complex II

Complex III

Complex IV

Tags

NGSS.HS-LS1-7

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Cellular Respiration Quiz (2)

Where does glycolysis occur?

Pyruvate processing (pyruvate → acetyl-CoA) occurs in the:

Where are the protein complexes of the electron transport chain (ETC) embedded?

Which electron carrier donates electrons to Complex I?

Which complex is the site where O₂ accepts electrons to form water?

Which complexes actively pump protons from the matrix toward the intermembrane space? (select best single answer)

FADH2 donates electrons primarily to:

The small, mobile carrier that shuttles electrons between complexes is:

The high concentration of protons generated by the ETC builds up in the:

ATP synthase produces ATP by using energy from:

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