A patient is diagnosed with non-severe hospital-acquired pneumonia. She states, “I’m allergic to penicillins, they always give me awful diarrhoea”. Which of the following is the most appropriate antibiotic to treat this infection?

• A. Amoxicillin

• B. Co-amoxiclav

• C. Doxycycline

• D. Erythromycin

• E. Levofloxacin

A 28-year-old pregnant woman is seen by her GP with symptoms of a urinary tract infection. She is 11 weeks pregnant with her first child. Microbiology results are not yet available but an atypical pathogen is not suspected. What pathogen is the most likely cause of this woman’s urinary tract infection?

• A. Chlamydia trachomatis

• B. Escherichia coli

• C. Gardnerella vaginalis

• D. Staphylococcus aureus

• E. Streptococcus pneumoniae

A 28-year-old pregnant woman is seen by her GP with symptoms of a urinary tract infection. She is 11 weeks pregnant with her first child. Microbiology results are not yet available but an atypical pathogen is not suspected. GP would like to prescribe antimicrobial treatment and would like your advice on which antibiotic would be most suitable.

• A. Amoxicillin 500mg capsules

• B. Cefalexin 250mg capsules

• C. Doxycycline 100mg capsules

• D. Nitrofurantoin 100mg MR capsules

• E. Trimethoprim 200mg tablets

A 28-year-old man is diagnosed with chlamydia and epididymitis; he is prescribed antibiotic treatment for 14 days. One month later during exercise he notices a sharp pain in the back of his leg. Cessation of activity and the use of NSAIDs did not relieve the symptoms. Upon examination, a diagnosis of partial tear of the Achilles tendon is made.

• A. Ampicillin

• B. Amoxicillin

• C. Cefalexin

• D. Co-amoxiclav

• E. Ofloxacin

A 47-year-old man comes to your clinic with swelling and redness on his forearm. He works at an animal shelter and was bitten by a cat. Although he washed the area, he is worried it is infected. Which antibiotic do you prescribe? He has no allergies

• A. Ampicillin

• B. Amoxicillin

• C. Cefalexin

• D. Co-amoxiclav

• E. Doxycycline

For initial treatment of Helicobacter pylori infection in penicillin allergic patients, a one-week triple therapy regimen comprises a proton pump inhibitor, clarithromycin, and which other antibiotic?

• A. Metronidazole

• B. Doxycycline

• C. Flucloxacillin

• D. Ofloxacin

• E. Cefalexin

A 68-year-old patient presents with an exacerbation of COPD. He is allergic to penicillin and is regularly prescribed: Aspirin 75mg, Bisoprolol 2.5mg, Lisinopril 5mg, Simvastatin 40mg. What is the most suitable antibiotic?

• A. Ampicillin

• B. Amoxicillin

• C. Cefalexin

• D. Co-amoxiclav

• E. Doxycycline

A 47-year-old woman presents with acute dysuria, frequency, urgency, and lower back pain. She takes prednisolone, carbocisteine, and salbutamol. Four days after starting antibiotics for a severe UTI, she develops abrupt severe ankle pain. Which antibiotic is likely associated with her new-onset symptoms?

• A. Nitrofurantoin

• B. Rifampicin

• C. Levofloxacin

• D. Trimethoprim

• E. Erythromycin

A 72-year-old patient presents with dysuria, urinary frequency, and urgency. eGFR=42mL/min. What is the most appropriate antibiotic?

• A. Nitrofurantoin

• B. Cefalexin

• C. Amoxicillin

• D. Ciprofloxacin

• E. Trimethoprim

A 6-year-old patient has recently been diagnosed with scarlet fever. What is the most appropriate first-line treatment?

• A. Doxycycline

• B. Phenoxymethylpenicillin

• C. No treatment – self-limiting

• D. Paracetamol

• E. Clarithromycin