Module 13, 14, & 15

Hemostasis, or the body's process of stopping bleeding following damage of blood vessels, begins with which stage?

• Vascular constriction

• Formation of a platelet plug (made of platelets and VWF)

• Blood coagulation and stable blood clot

T or F:

Thrombocytopenia is a deficient number of platelets (< 150,000) and is caused by issues with platelet production, like aplastic anemia, increased sequestration, via splenomegaly, or due to decreased survival, during DIC.

• True

• False

Which of the following options could cause thrombocytopenia (select all that apply)?

Hint: There are 4 correct options below...

• Aplastic anemia

• Splenomegaly

• DIC

• Secondary thrombocytosis

• Heparin-induced thrombocytopenia

An inherited condition that causes a deficiency, or malfunction, in Von Willebrand Factor (vWF) that leads to bleeding is called which of the following?

• Von Willebrand Disease

• Von Willebrand Syndrome

• Thrombotic thrombocytopenia purpura (TTP)

• Primary Thrombocytosis

This condition is defined by a systemic activation of a coagulation cascade that causes overactive clotting throughout the body, which then causes systemic bleeding due to a lack of platelets and clotting factors, eventually leading to organ failure.... This is the pathophysiology of what condition?

• Disseminated intravascular coagulation (DIC)

• Hemostasis

• Von Willebrand Syndrome

• Primary Thrombocytosis

This blood type is considered the "universal donor" because it does not contain AB antigens AND it is Rh negative.

• O-

• O+

• AB+

• AB-

Which form of anemia may result in a "sickling" of RBCs during periods of stress (low oxygen), resulting in severe pain, could result in stroke, blindness, enlargement of the spleen, acute chest syndrome, and even hemolysis (premature destruction of RBCs)

• Sickle Cell Disease

• Pernicious anemia

• Hemolytic anemia

• Thalassemias

Signs & symptoms of blood transfusion reactions include which of the following (select all that apply)?

• Flank pain

• Pruritus (intense itching)

• Acute respiratory distress

• Pulmonary edema

Which of the following lab values is most important when considering an individual's risk of infection?

• ANC < 500

• Platelets < 150,000

• WBCs < 5,000

• Low H&H

Which type of leukemia originates at myeloid blasts, is not acute, but has three separate phases of symptoms (chronic, accelerated, and blast), and has a genetic hallmark of the "Philadelphia Chromosome."

• Acute lymphocytic leukemia (ALL)

• Acute myelogenous leukemia (AML)

• Chronic lymphocytic leukemia (CLL)

• Chronic myelogenous leukemia (CML)