Endocrine Disruptors and Epigenetics and Heritable ADHD

The video discusses the increasing prevalence of neurodevelopmental disorders, focusing on ADHD. It explores the potential link between ADHD and endocrine disrupting chemicals (EDCs), particularly diethylstilbestrol (DES), which was used in pregnant women until 1971. A study in JAMA Pediatrics examines the association between DES exposure and ADHD in grandchildren, finding increased odds of ADHD diagnosis. Despite limitations, the study suggests an epigenetic cause for ADHD, highlighting the need for further research into other potential epigenetic factors affecting neurodevelopmental disorders.

What is one potential cause of ADHD mentioned in the video?

• Nutritional deficiencies

• Endocrine-disrupting chemicals

• Lack of physical activity

• Genetic mutations

What was the main focus of the study discussed in the video?

• The impact of diethylstilbestrol exposure on ADHD in grandchildren

• The influence of social interactions on ADHD

• The effects of diet on ADHD

• The role of exercise in preventing ADHD

What was the odds ratio for ADHD in grandchildren when grandmothers were exposed to diethylstilbestrol in the first trimester?

• 1.63

• 1.00

• 2.00

• 1.36

What is a major limitation of the study mentioned in the video?

• Inaccurate data collection methods

• Small sample size

• Reliance on maternal reports

• Lack of control group

What does the video suggest about future research directions?

• Improving dietary guidelines

• Increasing physical activity in children

• Exploring other epigenetic causes of neurodevelopmental disorders

• Focusing on genetic mutations